| QTL Map Information |
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| Chromosome: | 18 |
| QTL Peak Location: | 24.6 (cM) |
| QTL Span: | 23.66-23.86 (cM)
18.5-18.6 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | n/a |
| Threshold significance level: | Significant |
 |
P_values | <0.0001 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | NOD2 (nucleotide-binding oligomerization domain containing 2) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
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| Animals: | Animals were Chinese Holstein cows. |
| Breeds associated:
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| Design: | Animals were genotyped for five SNPs in CARD15 (NOD2) and analyzed for susceptibility to bovine tuberculosis. |
| Analysis: | Allele and genotype frequencies were compared between cases and controls using chi-square or Fisher's exact test. |
| Software: | SPSS, SHEsis |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Wang Y, Wang S, Liu T, Tu W, Li W, Dong G, Xu C, Qin B, Liu K, Yang J, Chai J, Shi X, Zhang Y |
| Affiliation: | College of Animal Science and Technology, Yunnan Agricultural University, Kunming, Yunnan Province, China |
| Title: | CARD15 Gene Polymorphisms Are Associated with Tuberculosis Susceptibility in Chinese Holstein Cows |
| Journal: | PloS one, 2015, 10(8): e0135085 |
| Links: |
PubMed | Abstract | List all data
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| Additional Information |
|---|
| Comments: | SNP 1648 |
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