| QTL Map Information |
|---|
| Chromosome: | 2 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
122.5-122.5 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs313663304 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | Comparison-wise |
| Threshold significance level: | Significant |
 |
P_values | 1.87E-6 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | n/a |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Chickens were from two different commercial laying hen populations suffering from two separate S. Gallinarum outbreaks of fowl typhoid. |
| Breeds associated:
n/a
|
| Design: | Genotypes were analyzed for association with fowl typhoid resistance. For the first outbreak, birds were genotyped using 11 SNPs and 3 microsatellite markers in a previously identified region on chromosome 5. For the second outbreak, birds were genotyped using the Affymetrix Axiom HD SNP array. |
| Analysis: | The GEMMA algorithm was used to perform GWAS analyses using a standard univariate linear mixed model. |
| Software: | ASReml 4.0, PLINK, GenABEL in R |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Psifidi A, Russell KM, Matika O, Sánchez-Molano E, Wigley P, Fulton JE, Stevens MP, Fife MS |
| Affiliation: | The Pirbright Institute, Surrey, United Kingdom |
| Title: | The Genomic Architecture of Fowl Typhoid Resistance in Commercial Layers |
| Journal: | Frontiers in genetics, 2018, 9: 519 |
| Links: |
PubMed | Abstract | List all data
| Edit |
| Additional Information |
|---|
| Comments: | Second outbreak; continuous phenotype |
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