Release 56
(Apr 24, 2025)

Whole genome analysis for QTL/association enrichment

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Version: Enrich S: beta v0.8
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Data:

Number of disease susceptibility traits:12
Number of QTL / associations found:479
Number of chromosomes where QTL / associations are found:26

Chi-squared (χ2) test: are disease susceptibility traits over-represented on some chromosomes?

Chromosomes Total χ2 df p-values FDR * Size of χ2
Chromosome X197.72832258.387494e-294.361497e-28
Chromosome 17.63224250.9996699.999997e-01
Chromosome 23.82428250.99999979.999997e-01
Chromosome 372.86820251.430596e-062.187970e-06
Chromosome 457.83688250.00020628462.681700e-04
Chromosome 5117.36084256.44863e-141.197603e-13
Chromosome 6135.49860253.761053e-177.522106e-17
Chromosome 7175.68240251.341114e-243.169906e-24
Chromosome 828.17504250.29985843.712533e-01
Chromosome 957.83688250.00020628462.681700e-04
Chromosome 1170.76376252.961593e-064.277857e-06
Chromosome 12197.72832258.387494e-294.361497e-28
Chromosome 133.82428250.99999979.999997e-01
Chromosome 14175.68240251.341114e-243.169906e-24
Chromosome 1519.15620250.78957018.925575e-01
Chromosome 16175.68240251.341114e-243.169906e-24
Chromosome 1784.99336251.845243e-082.998520e-08
Chromosome 1819.15620250.78957018.925575e-01
Chromosome 19197.72832258.387494e-294.361497e-28
Chromosome 2045940.92660259e-412.340000e-39
Chromosome 21175.68240251.341114e-243.169906e-24
Chromosome 22175.68240251.341114e-243.169906e-24
Chromosome 23175.68240251.341114e-243.169906e-24
Chromosome 24100.52580255.11613e-118.867959e-11
Chromosome 25135.49860253.761053e-177.522106e-17
Chromosome 26197.72832258.387494e-294.361497e-28

Chi-squared (χ2) test: Which of the 12 disease susceptibility traits are over-represented in the QTLdb

Traits Total χ2 df p-values FDR * Size of χ2
Bovine spongiform encephalopathy susceptibility 28.93753 11 0.002321171 2.532187e-03
Epidermolysis bullosa susceptibility 58.87503 11 1.499070e-08 1.798884e-08
Footrot susceptibility 167.70118 11 3.505305e-30 1.051592e-29
M. paratuberculosis antibody titer 79.64788 11 1.726144e-12 2.301525e-12
M. paratuberculosis susceptibility 107.11271 11 6.900833e-18 1.035125e-17
Maedi-Visna virus susceptibility 157.52836 11 4.295154e-28 1.030837e-27
Pleurisy 215.56657 11 4.327933e-40 2.596760e-39
Pneumonia susceptibility 131.65039 11 8.065663e-23 1.613133e-22
Salmonella abortusovis susceptibility 121.729 11 8.136374e-21 1.394807e-20
facial eczema susceptibility 262.30996 11 7.350778e-50 8.820934e-49
ovine pulmonary adenocarcinoma susceptibility 2.05988 11 0.9982742 9.982742e-01
scrapie susceptibility 196.67832 11 3.633986e-36 1.453594e-35

Correlations found between some of these traits for your reference

No correlation data found on these traits

Overall Test

Data Chi'Square Test Fisher's Exact Test
Number of chrom.:26 χ2=48700.885440
Number of traits:12 df=275
Number of QTLs:479 p-value=0

FOOT NOTE: * : FDR is short for "false discovery rate", representing the expected proportion of type I errors. A type I error is where you incorrectly reject the null hypothesis, i.e. you get a false positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where V = Number of Type I errors (false positives); R = Number of rejected hypotheses. Benjamini–Hochberg procedure is a practical way to estimate FDR.

 

© 2003-2025: USA · USDA · NRPSP8 · Program to Accelerate Animal Genomics Applications. Contact: Bioinformatics Team