Release 56
(Apr 24, 2025)

QTL 181609 Description:

Gene Information This is an eQTL
Gene name: glutathione peroxidase 8
Gene symbol: GPX8
 QTL Map Information
Chromosome:14
QTL Peak Location:n/a
QTL Span:n/a
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:SW210
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:Microsatellites
Analysis type:eQTL
Model tested:n/a
Test base:Comparison-wise
Threshold significance level:Significant
P_values4.10E-7
Dominance effect:n/a
Additive effect:n/a
Associated Gene:GPX8 (glutathione peroxidase 8)
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:A single large family of 4 F0 Duroc sires and 16 F0 Pietrain dams (F0), 56 F1 and 954 F2 animals from Michigan State University pig resource population.
     Breeds associated:
    Design:A whole genome expression microarray and an F2 pig resource population to conduct a global eQTL analysis in loin muscle tissue, and compared results to previously inferred phenotypic QTL (pQTL) on the same population.
    Analysis:Linear mixed model was fit to normalized log intensity data on an oligonucleotide-by-oligonucleotide basis comparing eQTL to previously published pQTL. Given a particular eQTL region, delimited by a 5 cM interval to each side of the peak, we computed a p-value for observing (by chance) an overlap as long as the one observed in each eQTL/pQTL region.
    Software: 
    Notes: 
    Links:Edit

     Reference
    Authors:Steibel Juan Pedro, Bates Ronald O, Rosa Guilherme J M, Tempelman Robert J, Rilington Valencia D, Ragavendran Ashok, Raney Nancy E, Ramos Antonio Marcos, Cardoso Fernando F, Edwards David B, Ernst Catherine W,
    Affiliation:Department of Animal Science, Michigan State University, East Lansing, Michigan, United States of America.
    Title:Genome-wide linkage analysis of global gene expression in loin muscle tissue identifies candidate genes in pigs.
    Journal:PloS one, 2011, 6 (2): e16766
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #21346809
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  • Cite this Data:

    Animal QTLdb: QTL181609 was published in 2011, and was curated into QTLdb on 2019-12-20. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:181609

     

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