Release 56
(Apr 24, 2025)

QTL 57488 Description:

 Trait Information
Trait name: Hemolytic complement activity (classical pathway) Vertebrate Trait Ontology: Complement classical pathway physiology trait
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: CH50 Clinical Measurement Ontology: n/a
 QTL Map Information
Chromosome:16
QTL Peak Location:27.7 (cM)
QTL Span:22.24-27.43 (cM)
13.1-20.0 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:Association
Model tested:Mendelian
Test base:n/a
Threshold significance level:Significant
P_values0.049
Dominance effect:n/a
Additive effect:n/a
Associated Gene:LOC100037951 (complement component C9)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were from an F2 resource population of Duroc x Berlin Miniature Pig.
     Breeds associated:
    n/a
    Design:Animals were genotyped for two SNPs in complement C9 and analyzed for hemolytic complement activity.
    Analysis:Mixed models were used.
    Software:SAS
    Notes: 
    Links:Edit

     Reference
    Authors:Khoa D V A, Wimmers K
    Affiliation:Institute for Genome Biology at the Leibniz Institute for Farm Animal Biology (FBN-dummerstorf), 18196 Dummerstorf, Germany
    Title:Genetic Association of the Porcine C9 Complement Component with Hemolytic Complement Activity
    Journal:Asian-Australasian journal of animal sciences, 2015, 28(9):1354-61
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:407C>G
    User inputs on reference #26194222
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  • Cite this Data:

    Animal QTLdb: QTL57488 was published in 2015, and was curated into QTLdb on 2015-08-20. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:57488

     

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