Release 56
(Apr 24, 2025)

This linkage-map based data has been obsolete
(see Release notes 51, 52, 53). Information
provided here is only for retrospective online
support of publications that used this data.

QTL 7234 Description:

 Trait Information
Trait name: Melanoma susceptibility Vertebrate Trait Ontology: n/a
Reported name: Melanoma susceptibility Product Trait Ontology: n/a
Symbol: MELAN Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:8
QTL Peak Location:58.2 (cM)
QTL Span:53.68-54.15 (cM)
41.9-42.1 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:SW1953
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:Microsatellites
Analysis type:QTL
Model tested:Mendelian
Test base:Chromosome-wise
Threshold significance level:Significant
P_values0.0124
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

User inputs on QTL #7234
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  •  QTL Experiment in Brief
    Animals:Animals were Sinclair Swine that develop cutaneous malignant melanoma.
     Breeds associated:
    n/a
    Design:Animals were genotyped for 7 microsatellite markers each on chromosomes 6 and 8 and analyzed for tumor development.
    Analysis:Interval mapping methods were used to search for the tumor initiator locus and for loci affecting the virulence of the disease.
    Software: 
    Notes: 
    Links:Edit

     Reference
    Authors:Gomez-Raya, L; Okomo-Adhiambo, M; Beattie, C; Osborne, K; Rink, A; Rauw, W M
    Affiliation:Department of Animal Biotechnology, University of Nevada, Reno, Nevada 89557, USA
    Title:Modeling inheritance of malignant melanoma with DNA markers in Sinclair swine.
    Journal:Genetics, 2007, 176 (1): 585-97
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:Tumors at birth
    User inputs on reference #17513891
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  • Cite this Data:

    Animal QTLdb: QTL7234 was published in 2007, and was curated into QTLdb on 2009-08-20. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:7234

     

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